Direct Electron Transfer: An Approach for Electrochemical Biosensors with Higher Selectivity and Sensitivity
نویسندگان
چکیده
A abordagem mais promissora para o desenvolvimento de biossensores eletroquímicos é a busca da comunicação elétrica direta entre as biomoléculas e a superfície do eletrodo. Esta revisão apresenta as principais abordagens, estratégias e avanços no desenvolvimento de biossensores eletroquímicos de terceira geração. Os temas discutidos englobam uma breve descrição sobre os fundamentos do fenômeno de transferência de elétrons e sobre o desenvolvimento de biossensores amperométricos (diferentes tipos e novas técnicas de imobilização orientada de enzimas). Um enfoque especial foi dado para as enzimas e proteínas redox capazes de eletrocatalisar reações via transferência direta de elétrons. Também foram apresentadas e discutidas as aplicações analíticas e tendências futuras dos biossensores de terceira geração.
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